Andrew B Singleton Selected Research

Synucleinopathies

10/2020	LRRK2 mediates microglial neurotoxicity via NFATc2 in rodent models of synucleinopathies.
1/2020	Disease modification and biomarker development in Parkinson disease: Revision or reconstruction?

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Andrew B Singleton Research Topics

Disease

47	Parkinson Disease (Parkinson's Disease) 11/2023 - 11/2002
15	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2024 - 05/2006
13	Parkinsonian Disorders (Parkinsonism) 01/2022 - 04/2003
10	Alzheimer Disease (Alzheimer's Disease) 06/2023 - 11/2010
7	Cognitive Dysfunction 10/2021 - 09/2010
6	Dementia (Dementias) 10/2023 - 01/2002
5	Frontotemporal Dementia (Semantic Dementia) 01/2016 - 05/2006
4	Tremor (Tremors) 10/2016 - 11/2004
3	Disease Progression 12/2022 - 03/2013
3	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 12/2021 - 01/2012
3	Inflammation (Inflammations) 01/2021 - 12/2016
3	Multiple System Atrophy 10/2020 - 10/2011
3	Lewy Body Disease (Lewy Body Dementia) 01/2020 - 02/2005
3	Ischemic Stroke 07/2015 - 01/2008
3	Stroke (Strokes) 07/2015 - 01/2008
3	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 02/2015 - 04/2003
3	Dystonia (Limb Dystonia) 03/2008 - 08/2004
2	Tauopathies 04/2023 - 07/2013
2	Constipation 01/2023 - 10/2021
2	Synucleinopathies 10/2020 - 01/2020
2	Ataxia (Dyssynergia) 11/2017 - 02/2013
2	Brown-Vialetto-Van Laere syndrome 11/2017 - 09/2012
2	Coronary Disease (Coronary Heart Disease) 05/2013 - 08/2011
2	Gaucher Disease (Gaucher's Disease) 02/2013 - 08/2006
1	Olfaction Disorders (Cacosmia) 10/2023
1	Neurodegeneration with brain iron accumulation (NBIA) 04/2023
1	Dry Eye Syndromes (Dry Eye Syndrome) 01/2023
1	Anosmia 01/2023
1	Fatigue 01/2023
1	Neoplasms (Cancer) 01/2023
1	Weight Loss (Weight Reduction) 01/2023
1	REM Sleep Behavior Disorder 10/2021
1	Dyskinesias (Dyskinesia) 01/2021
1	Sleep Initiation and Maintenance Disorders (Insomnia) 12/2019
1	Myocardial Infarction 01/2019
1	Hereditary Diffuse Leukoencephalopathy with Spheroids 01/2018
1	Infarction (Infarctions) 01/2018
1	Leukoencephalopathies 01/2018
1	Metachromatic Leukodystrophy (Sulfatide Lipidosis) 01/2018
1	Mitochondrial Diseases (Mitochondrial Disease) 11/2017
1	Optic Atrophy 11/2017
1	Rheumatoid Arthritis 01/2017
1	Ulcerative Colitis 01/2017
1	Autoimmune Diseases (Autoimmune Disease) 01/2017
1	Crohn Disease (Crohn's Disease) 01/2017

Drug/Important Bio-Agent (IBA)

11	Proteins (Proteins, Gene)FDA Link 01/2023 - 11/2004
10	Biomarkers (Surrogate Marker)IBA 06/2023 - 10/2015
9	Phosphotransferases (Kinase)IBA 01/2022 - 12/2004
8	SynucleinsIBA 10/2020 - 10/2011
7	Leucine (L-Leucine)FDA Link 01/2022 - 03/2005
7	Levodopa (L Dopa)FDA LinkGeneric 10/2016 - 04/2003
4	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 04/2008
4	Amyloid (Amyloid Fibrils)IBA 01/2023 - 03/2013
4	RNA (Ribonucleic Acid)IBA 01/2023 - 05/2014
4	Apolipoproteins E (ApoE)IBA 01/2021 - 05/2012
4	Glucosylceramidase (Glucocerebrosidase)IBA 01/2020 - 08/2006
4	alpha-SynucleinIBA 12/2010 - 02/2005
3	Dopamine (Intropin)FDA LinkGeneric 01/2022 - 11/2002
3	EnzymesIBA 01/2020 - 08/2006
3	LipidsIBA 09/2019 - 01/2015
2	Protein Isoforms (Isoforms)IBA 04/2023 - 07/2013
2	IronIBA 04/2023 - 09/2010
2	NucleotidesIBA 01/2023 - 02/2015
2	Protein AggregatesIBA 01/2020 - 05/2006
2	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2019 - 11/2015
2	Riboflavin (Vitamin B2)FDA LinkGeneric 11/2017 - 09/2012
2	Valosin Containing ProteinIBA 11/2016 - 01/2012
2	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 09/2014 - 09/2012
2	CholesterolIBA 10/2013 - 11/2010
2	Mitochondrial DNA (mtDNA)IBA 05/2013 - 03/2013
1	Adenosine Monophosphate (AMP)IBA 11/2023
1	Soaps (Soap)IBA 10/2023
1	Amyloid beta-PeptidesIBA 06/2023
1	VaccinesIBA 01/2023
1	ORALIT (ORS)IBA 01/2023
1	Indicators and Reagents (Reagents)IBA 12/2022
1	Lipoprotein Lipase (Diacylglycerol Lipase)IBA 01/2022
1	Coffee FDA Link 01/2022
1	EndocannabinoidsIBA 01/2022
1	HLA-DRB1 Chains (HLA DRB1)IBA 01/2022
1	Antidepressive Agents (Antidepressants)IBA 10/2021
1	SolutionsIBA 01/2021
1	ProgranulinsIBA 01/2021
1	Adrenergic Receptors (Adrenergic Receptor)IBA 12/2019
1	Carrier Proteins (Binding Protein)IBA 01/2019
1	CytosineIBA 01/2019
1	Hormones (Hormone)IBA 01/2019
1	Phosphates (Orthophosphate)IBA 01/2019
1	GuanineIBA 01/2019
1	Eukaryotic Initiation Factor-2B (Eukaryotic Initiation Factor 2B)IBA 01/2018
1	EstersIBA 11/2017
1	Vitamin D FDA LinkGeneric 08/2017
1	25-hydroxyvitamin DIBA 08/2017
1	HLA-DRB5 Chains (HLA DRB5)IBA 01/2017
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2017
1	ClathrinIBA 01/2017

Therapy/Procedure

11	Therapeutics 10/2023 - 03/2008
3	Precision Medicine 01/2024 - 01/2020
1	Activities of Daily Living (ADL) 01/2021
1	Mechanical Ventilators (Ventilator) 11/2017